Detection of malignant lymphoma with invasion in liver and spleen using PET/CT imaging
- VernacularTitle:PET/CT诊断恶性淋巴瘤对肝和(或)脾的侵犯
- Author:
Xin-lu, WANG
;
Xiang-dong, LI
;
Jiang-tao, QUAN
;
Xi, OUYANG
;
Chao, CAI
;
Hui, ZHENG
;
Ji-lin, YIN
- Publication Type:Journal Article
- Keywords:
Lymphoma;
Neoplasm invasiveness;
Liver;
Spleen;
Tomography,emission-computed;
Tomography,X-ray computed;
Deoxyglucose
- From:Chinese Journal of Nuclear Medicine
2008;28(3):164-167
- CountryChina
- Language:Chinese
-
Abstract:
Objective The detection of malignant lymphoma with invasion in liver and spleen using PET/CT has not been well documented in the literature. This study aimed to investigate the usefulness of PET/CT in this regard and to compare it with plain CT. Methods Forty-one pathologically confirmed malignant lymphoma patients with liver and spleen invasion were recruited into this study. Among all patients, there were 38 non-Hodgkin's lymphoma (NHL), 2 Hodgkin's lymphoma (HL) and 1 gastric mucosa associated lymphoma. PET/CT imaging was recorded 1h after injection of 296～444 MBq 18F-fluorodeoxyglucose (FDG). Results (1) There were 30(30/41) patients with liver invasion, including hepatic nodules, mass and portal nodes. The mass was large to invade surrounding liver parenchyma. (2) There were 23(23/41) patients with spleen invasion. The spleen was enlarged and demonstrated diffused hyper-metabolism. (3) Other invasion included: lung (n=13), cortical bone and marrow (n=12), stomach (n=9), pleural (n=6), and subcutaneous soft tissue (n=5) and so on. Conclusion PET/CT could accurately diagnose the invasion in liver and spleen of malignant lymphoma, which was of potential role on the diagnosis and staging of lymphoma.
