Current progression in pharmacotherapeutics of fungal keratitis
10.3969/j.issn.1003-0808.2010.02.021
- VernacularTitle:真菌性角膜炎的药物治疗进展
- Author:
Linghui, QU
;
Liangmao LI
- Publication Type:Journal Article
- Keywords:
keratitis;
eye infections;
fungus;
pharmacotherapeutics
- From:Chinese Ophthalmic Research
2010;28(2):178-182
- CountryChina
- Language:Chinese
-
Abstract:
Fungal keratitis is the first common infectious corneal disease and has become the main cause of blindness in China.Along with the intensive explore for the pathogenic mechanisms,the significant progress has been achieved in the pharmacotherapeutics.For lowering its blindnessrate,it is imperative to the study on increasing therapeutic option and enhancing therapeutic efficacy.This review summarizes the current advance in clinical use in ophthalmology of novel antifungal agents,including new azoles such as voriconazole and posaconazole,and echinocandins such as caspofungin and micafungin.This article also reviews the progress of administration routes for the management of recalcitrant fungal keratitis,including subconjunctival,interstromal,intracameral and intravitreal injection.
