Clinical significance of DNA haploid analysis for malignant degree and prognosis assessment of breast carcinoma
- VernacularTitle:DNA倍体分析对乳腺癌恶性程度及预后评估的临床意义
- Author:
yong, ZHANG
;
qiang, XUE
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
DNA;
Ploidies;
Prognosis
- From:
Journal of International Oncology
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of DNA haploid analysis for malignant degree and prognosis assessment of breast carcinoma. Methods Highclarity Colourful Pathological Analysis System-1000( HPIAS-1000) was used to analyze the DNA haploid of 120 breast carcinoma patients who had been followed up for more than 5 years. All patients were divided into three groups according to histology. 48 advanced differentiation cases, 44 middle differentiation cases and 28 low differentiation cases. Then DNA haploid analysis was made,that is diploid(2C) ,3 - 4C,aneuploid(AN). Results Except for 3 -4C,there were significant differences betweenⅠandⅡgrade ,ⅡandⅢgrade,ⅠandⅢgrade( P
