Correlation analysis between diabetic macular edema and serum E-selectin
10.3980/j.issn.1672-5123.2014.09.43
- VernacularTitle:糖尿病性黄斑水肿与血清 E-选择素的相关性分析
- Author:
Zhi-Hong, ZHANG
;
Kun-Li, ZHANG
- Publication Type:Journal Article
- Keywords:
diabetic macular edema;
serum soluble E-selectin;
microalbuminuria
- From:
International Eye Science
2014;(9):1697-1698
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the relationship between diabetic macular edema (DME) and serum E-selectin level.
●METHODS: Totally 90 patients with diabetic retinopathy in our hospital from October 2009 to October 2013 were observed. Retrospective analysis of the correlation between macular edema degree and serum soluble E -selectin ( sE - sel ). Ninety patients with diabetic retinopathy were divided into two groups: DME group and non - DME group. The level of sE - sel and microalbuminuria (MA) of two groups were determined and compared.
●RESULTS: There was significant difference in MA, sE-sel levels of groups ( P < 0. 05). The value of diabetic retinopathy patients with sE - sel and MA, FBG were positively correlated ( r = 0. 728, P < 0. 05; r = 0. 651, P <0. 05).
●CONCLUSlON: Elevated levels of sE-sel is a risk factor for diabetic macular edema, and sE-sel was involved in the pathogenesis of diabetic microangiopathy.