Clinical observation of diabetic retinopathy after transplantation of autologous stem cell in diabetic patients
10.3980/j.issn.1672-5123.2014.09.45
- VernacularTitle:自体干细胞移植术后糖尿病视网膜病变的变化分析
- Author:
Xiao-Lin, HAO
;
Xiu-Ling, YE
;
Zhong-Chen, ZHANG
- Publication Type:Journal Article
- Keywords:
diabetic retinopathy;
autologous stem cell transplantation;
diabetes
- From:
International Eye Science
2014;(9):1702-1704
- CountryChina
- Language:Chinese
-
Abstract:
To observe the effect of autologous stem cell transplantation in diabetic retinopathy.
●METHODS:Totally 58 cases (116 eyes) who underwent autologous stem cell transplantation were confirmed as no diabetic retinopathy (18 eyes), mild non-proliferative diabetic retinopathy (NPDR) (41 eyes), mid-level NPDR (51 eyes); severe NPDR (6 eyes) by ophthalmoscope directly or indirectly and fluorescence fundus angiography (FFA ). Follow - up was 6 - 12mo, the changes of retinopathy were observed.
●RESULTS: The total effective rate of vision and retinopathy was 84. 4%, 76. 7%. The results of severe NPDR was statistically worse than the other groups ( P <0. 05).
●CONCLUSlON: The stable blood glucose level and improved pancreatic function after autologous stem cell transplantation might be helpful in diabetic retinopathy, the long effects need to be researched further.
