Analysis of curative effect and drug tolerance in the treatment of severe bacterial oculopathy by levofloxacin
10.3980/j.issn.1672-5123.2014.09.47
- VernacularTitle:左氧氟沙星治疗重症细菌性眼病的疗效及耐药性
- Author:
Su-Hua, XIAO
- Publication Type:Journal Article
- Keywords:
levofloxacin;
keratitis;
conjunctivitis;
drug tolerance
- From:
International Eye Science
2014;(9):1707-1709
- CountryChina
- Language:Chinese
-
Abstract:
To evaluate the curative effect and drug tolerance in the treatment of severe bacterial keratitis and conjunctivitis by levofloxacin.
●METHODS: Totally 195 patients with severe bacterial keratitis and conjunctivitis were included in this study. Based on the sequence of enrollment, they were randomly divided into three groups: group A ( 65 patients) received levofloxacin, group B ( 65 patients) received suture method under microscope, group C received suture method with loupe besides the same basic operative treatment in the two groups. The curative effect and drug tolerance were observed and compared statistically.
●RESULTS: ln group A, 54 cases were cured, in the rate of 83. 1%, 7 cases ( 10. 8%) were excellent, 3 cases (4. 6%) were valid, 1 case (1. 5%) was invalid. ln group B, 25 cases (38. 5%) were cured, 6 cases (9. 2%) were excellent, 23 cases (35. 4%) were valid, 11 cases (16. 9%) were invalid. ln group C, 4 cases (6. 2%) were cured, 3 cases (4. 6%) were excellent, 36 cases (55. 4%) were valid, 22 cases (33. 8%) were invalid. The curative effect and drug tolerance among groups had obvious differences (P<0. 05).
●CONCLUSlON: Levofloxaoin is effective and safe for the treatment of bacterial conjunctivitis and keratitis, which is not resistant and worthy of promotion.
