Effect of phacoemulsification on corneal endothelium of cataract with lupus nephritis
10.3980/j.issn.1672-5123.2014.09.32
- VernacularTitle:狼疮性肾炎患者白内障超声乳化术后角膜内皮细胞的观察
- Author:
Fen, YE
;
Ying-Ying, CHENG
;
Yan, WU
;
Zhen-Ping, HUANG
- Publication Type:Journal Article
- Keywords:
cataract;
phacoemulsification;
lupus nephritis;
corneal endothelium
- From:
International Eye Science
2014;(9):1667-1669
- CountryChina
- Language:Chinese
-
Abstract:
To evaluate the influence of phacoemulsification on corneal endothelium of senile cataract with lupus nephritis (LN).
●METHODS:This clinical trial involved 40 cataract patients with lupus nephritis (40 eyes), and 50 cases (50 eyes) without lupus nephritis. All of them underwent phacoemulsification+lOL implantation. The parameters of corneal endothelial cell including central corneal endothelium cell density ( CED ), average area of endothelial cell ( AVE) and coefficient of variation ( CV) were recorded by corneal endothelial microscope pre -operation and at one month after operation. The data were analyzed by SPSS 13. 0 statistical software.
● RESULTS: Both LN group and control group, the morphology of coneal endothelial was statistical significant differences between pre - operation and 1mo postoperation. The CED was lower, AVE and CV were higher ( P < 0. 05, respectively). A significant decrease in CED was seen in the LN group than did in the control group (P < 0. 05). Compared to control group,the post -operative AVE and CV in LN group was significantly increased (P<0. 05).
● CONCLUSlON: The corneal endothelial cell in lupus nephritis patients is more fragile. Safe and reliable operation should be selected for these patients.
