Clinical observation of ondansetron administration at different time in preventing nausea and vomiting after pediatric strabismus surgery
10.3980/j.issn.1672-5123.2014.06.58
- VernacularTitle:不同时间给予昂丹司琼预防小儿斜视术后恶心呕吐的临床观察
- Author:
Huai-Gang, LIU
;
Xiao-Jing, LI
;
Jian-Jun, LI
- Publication Type:Journal Article
- Keywords:
ondansetron;
pediatric strabismus surgery;
nausea and vomiting
- From:
International Eye Science
2014;(6):1177-1178
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To observe the efficacy of ondansetron by intravenous injection at different time in preventing nausea and vomiting after pediatric strabismus surgery.METHODS: Totally 90 children aged 3 - 11y were randomly selected for pediatric strabismus surgery from June 2013 to August 2013 in our hospital. The ASA grade of all children were Ⅰ - II. Children were randomly divided into three groups with 30 cases each. Group A received intravenous drip of ondansetron 0. 1mg/kg before surgery. Group B received intravenous drip of ondansetron 0. 1mg/kg after surgery. Group C as control group was not given ondansetron. The number and severity of nausea and vomiting were observed within 24h after surgery.
RESULTS: There were no statistical significance in patients' gender, weight, age, duration of anesthesia, ketamine dosage and vital signs intraoperative between the three groups ( P > 0. 05 ). The incidence rate of postoperative nausea and vomiting ( PONV) of group A and B were significantly lower than group C (P<0. 05). The incidence rate of PONV of group A and group B have no significant difference (P>0. 05).
CONCLUSION:Using ondansetron is effective and safe in preventing PONV before and at the end of the pediatric strabismus surgery, which can also improve safety and be lower cost. It is a worthy promoting antiemetic approach for eye surgery.
