Retinal pigment epithelial detachment post radiation therapy in metastatic ocular infiltration of non-Hodgkin's lymphoma: a case report
10.3969/j.issn.1672-5123.2010.04.004
- VernacularTitle:非霍奇金淋巴瘤转移性眼浸润放射治疗后视网膜色素上皮脱离1例
- Author:
Muzaliha Mohd NOR
;
Roslinah MUJI
;
Zunaina EMBONG
;
Bakiah SHAHARUDDIN
;
Shatriah ISMAIL
- Publication Type:Journal Article
- Keywords:
non-Hodgkin's lymphoma;
metastatic ocular infiltration;
involved field radiation therapy;
retinal pigment epithelial detachment
- From:
International Eye Science
2010;10(4):623-626
- CountryChina
- Language:Chinese
-
Abstract:
A 32-year-old lady, diagnosed with anaplastic large cell non-Hodgkin's lymphoma of the mediastinum, presented with bilateral floaters and reduced right eye vision 3 years post chemotherapy. Ophthalmic examination revealed bilateral panuveitis with multiple deep seated choroidal lesions in the left eye. Computed tomography scanning of the orbit showed enhancing and bulky optic nerve sheath at the retrobulbar part of both optic nerves. The patient was treated with involved field radiation therapy of the orbit, with cumulative dose of 30Gy. Eight months post radiation therapy, she developed retinal pigment epithelial detachment at the macula and deep chorioretinal degeneration at superotemporal and inferonasal regions of the right fundus. There was evidence of vitreoretinal traction at the margin of chorioretinal degeneration areas, thus barricade lasers were performed in the affected eye. Her visual acuity remains 6/6 in both eyes. Retinal pigment epithelial detachment is a possible complication of radiation therapy in non-Hodgkin's lymphoma with intraocular metastasis. It is essential to alert the managing ophthalmologists about this rare complication.
