Clinical spectrum of 15 patients with HIV-related ocular involvement in Tehran
10.3969/j.issn.1672-5123.2011.02.02
- VernacularTitle:德黑兰15例HIV患者眼部病变的临床特点
- Author:
Abdollahi ALI
;
Heidari-Bateni GIV
;
Zarei, REZA
;
Kheirandish PARASTOU
;
Malekmadani MOHAMMADHOSEIN
;
Mohraz MINOO
;
Abdollahi MARYAM
;
Rajabi Taher MOHAMMAD
- Publication Type:Journal Article
- Keywords:
HIV;
ocular involvement;
highly active anti-retroviral therapy
- From:
International Eye Science
2011;11(2):199-204
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To determine the frequency of HIV-related ocular involvement and to describe the characteristics of involvement in a special clinic in Tehran.METHODS: In this cross sectional study, 141 patients (125 male and 16 female, 282 eyes) of HIV-infected patients with various stages of HIV infection that were referred to Center of behavioral diseases were evaluated during a period of 7 months. Every patient had a complete profile including demographic data, method of HIV transmission, recent CD4 T cell lymphocyte count, serological studies for common sexual or blood-born viruses and toxoplasmosis, history of antiretroviral therapy, and associated systemic disease. RESULTS: A total of 141 patients were evaluated. HIV-related ocular involvement was detected in 15 patients (10.6%), including 3 mycobacterium tuberculosis-related choroiditis, 2 cytomegalovirus retinitis, 2 retinal toxoplasmosis, 2 herpes simplex virus-related lesions, 1 HIV-associated retinopathy, 1 herpes zoster ophthalmicus, 1 undetermined vitritis, and 3 cases of cranial nerve involvement including 2 cases of gaze palsy and 1 case of papilitis. In our study, mean CD4 T cell lymphocyte count was fewer in patients with ocular involvement than in patients without ocular involvement (204.7±123.8 vs 403.7±339.7, P=0.029), but there was no difference in other possible associated factors between two groups.lesions are the most common HIV-related ocular involvements in Tehran that is different from those of recent publications in developed countries.
