Amniotic membrane transplantation for the managenment of earlier Mooren's ulcer
- VernacularTitle:羊膜移植治疗早期蚕蚀性角膜溃疡的临床研究
- Author:
Dong-Ling, JIANG
;
Ming-Chang, ZHANG
;
Yan-Hua, HU
- Publication Type:Journal Article
- Keywords:
Mooren's ulcer,earlier;
amniotic membrane transplantation
- From:
International Eye Science
2006;6(1):9-12
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the efficacy and safety of annular conjunctival excision combined with amniotic membrane transplantation for the management of earlier Mooren's ulcer.METHODS: Thirty eyes (24 patients) with earlier Mooren's ulcer were treated with this method, followed-up for 5-30mo. The characteristic of these patients was localized periphery corneal ulcer: the ulcer involved 30-120° corneal limbus with depth of 1/3-1/2 cornealthickness and width of 2-5mm.RESULTS: After surgery, symptoms subsided remarkably and immediately in all patients,and almost disappeared after stitches were removed. Corneal melts were controlled. At postoperative 2-3mo, the corneal thickness of the ulcer area became almost stable, which in some patients recovered normal and in others were still thinner than normal, and the average increase was about 1/3 of the corneal thickness. Corneal transparence and vision were improved. During follow-up, no severe complications or recurrence were noted.CONCLUSION: Conjunctival peritomy combined with amniotic membrane transplantation is an effective and safe method for the treatment of earlier Mooren's ulcer.
