A follow-up study on keratopathy in eyes after radiation therapy for nasopharyngeal carcinoma
- VernacularTitle:鼻咽癌放疗性角膜损伤的跟踪研究
- Author:
Qing-Ping, ZHANG
;
Chang-Hua, YE
;
Guang-Wu, HUANG
;
Cheng-Xi, XIE
;
Wei-Wei, ZHOU
;
Lin, RUAN
- Publication Type:Journal Article
- Keywords:
keratopathy;
ocular surface disease;
radiation therapy;
nasopharyngeal carcinoma
- From:
International Eye Science
2006;6(4):755-757
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the ocular complication after radiation therapy for nasopharyngeal carcinoma(NPC).METHODS: The authors performed a previous study on keratopathy in 213 NPC patients who received first stage radiation and had at least 10 months of follow-up. These patients were categorized into three groups depending on NPC clinic stages. Rates and proportions of keratopathy occurring in these groups were compared and analyzed with Chi-square Test and Spearman rank correlation coefficient.RESULTS: Radiation keratopathy developed in 19 patients, about 8.9% (19/213). The latency value was 3 to 30days. The effect of NPC clinic stages and radiation did on the development of keratopathy was not statistically significant (P＞0.05).CONCLUSION: The NPC clinic stages and radiation doses plays few effects on the development of keratopathy. It may play a key role that corneal nerves damage induced ocular surface diseases. It can not be excluded that individuals have different sensitivities to radiation.
