Mesenchymal chondrosarcoma of the orbit: report of a case and review of the literature
- VernacularTitle:眼眶间叶性软骨肉瘤——病例报告与文献复习
- Author:
Hong-Bin, LÜ
;
Yu-Li, YANG
;
Qing-Li, LUO
;
Wei-Min, HE
- Publication Type:Journal Article
- Keywords:
mesenchymal chondrosarcoma;
histopa-thology;
immunohistochemistry
- From:
International Eye Science
2008;8(8):1524-1527
- CountryChina
- Language:Chinese
-
Abstract:
· AIM: To report a rare case of mesenchymalchondrosarcoma in the orbit and to explore its clinicmanifestations, pathologic characters, management andprognosis. · METHODS: We report a case of mesenchymalchondrosarcoma of the orbit. The clinical materials,including ophthalmological examination, computed tomo-graphy scan of the orbit, histopathology and immunohis-tochemistry of the biopsy specimen was reported, and itspertinent literatures were reviewed.· RESULTS: A 36-year-old female was seen with proptosisand decreased vision. Histopathology demonstrated anadmixture of undifferentiated mesenchymal cells andislands of mature hyaline cartilage. Immunohistochemicalstudies revealed positivity for vimentin and S-100, whichwas consistent with the diagnosis of mesenchymalchondrosarcoma.· CONCLUSION: Mesenchymal chondrosarcoma in theorbit is extremely rare malignant tumor. Multi-modalitytreatments (surgery, chemotherapy and radiotherapy)may lead to long-term survival.
