Analysis of the correlation between autofluorescence and central vision at advanced stage of the classical retinitis pigmentosa
10.3969/j.issn.1672-5123.2009.04.003
- VernacularTitle:视网膜色素变性晚期自发荧光与中心视力相关性分析
- Author:
Fu-Bin, WANG
- Publication Type:Journal Article
- Keywords:
retinitis pigmentosa;
autofluorescence;
central vision;
advanced stage
- From:
International Eye Science
2009;09(4):616-618
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate autofluorescence (AF) images of classical retinitis pigmentosa (RP) at advanced stage correlated with central vision. METHODS: Thirty-seven patients (70 eyes) with classical RP at advanced stage were observed. AF imaging was performed using a Heidelberg Retina Angiograph 2 ( HRA-2) scanning laser system with the field 30°, the pixels 1 536×1 536 and pupil diameters >6mm. Some patients underwent automated static peri-metry and the flash electroretinogram(FERG) were performed according to International Society for Clinical Electrophysiology of Vision( ISCEV) standard. RESULTS: All patients were classified as four patterns according to their manifestation of AF they were intact, patchy, solitary island and central hypofluorescence patterns. Different pattern showed different central vision. The data demonstrate high correlation between the central cone function and AF changes of the fundus. There is significant correlation (n= 57, r= 0.385,P＜0.01) between central vision and the AF area and between age and AF area (n= 57, r= -2.67,P＜0.05).CONCLUSION: AF images is valuable to the monitoring of central cone function and in predicting retention of central vision. The changes of AF images correlated with central vision and different pattern showed different vision.
