Association of serum lipid profile with retinal hard exudates among patients with type 2 diabetes mellitus
10.3969/j.issn.1672-5123.2009.04.006
- VernacularTitle:血清血脂分析结果与2型糖尿病患者视网膜硬性渗出的关系
- Author:
Amelah Mohamed Abdul QADER
;
Zunaina EMBONG
;
Bakiah SHAHARUDDIN
;
Shahrul Bariyah Sahul HAMID
;
Shatriah ISMAIL
- Publication Type:Journal Article
- Keywords:
retinal hard exudates;
lipid profile;
diabetes mellitus type 2
- From:
International Eye Science
2009;09(4):627-630
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the association between lipid profile and retinal hard exudates in diabetic retinopathy (DR) and the association between oxidized-LDL with systemic diseases among type 2 diabetic patients.another 40 patients without DR. Demographic data was collected and comprehensive ocular examination was performed. Nine mL venous blood was taken for fasting serum cholesterol, triglycerides, HDL, LDL, ox-LDL, and for HbA1C. Compared to patients without retinopathy 5.0±1.03mmol/L (P=0.001). The mean serum LDL was 3.6±1.69mmol/L in retinopathy group compared to 3.0±1.02mmol/L in the contol group (P=0.005). There was a higher concentration of serum cholesterol, triglyceride and LDL in patients with severe retinal hard exudates compared to those with mild and moderate, however it was not statistically significant (P=0.082, 0.116, 0.218) respectively. The mean serum oxidized-LDL concentration was higher in DR with severe retinal hard exudates compared to mild and moderate. There was no statistically significant difference in the mean oxidized LDL with other systemic diseases or duration of diabetes.and LDL with DR. However there was no association between serum lipid profile with the severity of retinal hard exudates. Serum ox-LDL was also not associated with DR and other systemic co-morbidities in our study.
