Spontaneous rodent models of diabetes and diabetic retinopathy
10.3969/j.issn.1672-5123.2010.03.004
- VernacularTitle:糖尿病和糖尿病视网膜病变相关的自然发病啮齿动物模型
- Author:
Cai-Rui, LI
;
Shu-Guang, SUN
- Publication Type:Journal Article
- Keywords:
rodent model;
diabetes mellitus;
diabetic retinopathy
- From:
International Eye Science
2010;10(3):417-420
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes is a complex and heterogeneous disorder presently affecting more than 100 million people worldwide and causing serious socio-economic problems. Spontaneous rodent models of diabetes mellitus have proved invaluable in understanding the pathogenesis, complications, and genetic or environmental influences that increase the risks of diabetes. We have reviewed here in the development and characterization of spontaneous rodent models that displayed most features commonly associated with diabetic retinopathy.
