Ocular manifestations of Alport syndrome
10.3969/j.issn.1672-5123.2010.05.004
- VernacularTitle:Alport综合征眼部临床表现分析
- Author:
Jian-Min, XU
;
Shi-Sheng, ZHANG
;
Qiong, ZHANG
;
Ying-Ming, ZHOU
;
Cai-Hong, ZHU
;
Jian, GE
;
Ling, WANG
- Publication Type:Journal Article
- Keywords:
Alport syndrome;
anterior lenticonus;
macular flecks
- From:
International Eye Science
2010;10(5):835-837
- CountryChina
- Language:Chinese
-
Abstract:
·AIM: To analyze the clinical manifestation of Alport syndrome, especially the ocular features.·METHODS: The physical, ophthalmologic and audiologic examination results of thirty two patients with Alport syndrome were analyzed retrospectively.·RESULTS: Thirty (93.7%) patients had some family history. All patients had renal disease: eighteen(56.3%) patients with chronic renal failure, four(12.5%) patients with renal insufficiency, and the other ten(31.3%) patients with hematuria. Twenty (62.5%) patients had sensorineural deafness. Thirteen (40.6%) patients had ocular deformity, five(15.6%) patients had typical ocular changes: three patients with anterior lenticonus, and two patients with macular flecks.·CONCLUSION: Ocular anomalies are not requisite for the diagnosis of Alport syndrome. But its typical ocular features should be recognized by the ophthalmologists which supports the diagnosis.
