Clinical Efficacy of Organ-Preserving Pancreatectomy for Benign or Low-Grade Malignant Potential Lesion.
10.3346/jkms.2010.25.1.97
- Author:
Seung Eun LEE
1
;
Jin Young JANG
;
Dae Wook HWANG
;
Kuhn Uk LEE
;
Sun Whe KIM
Author Information
1. Department of Surgery, Seoul National University, College of Medicine, Seoul, Korea. sunkim@plaza.snu.ac.kr
- Publication Type:Original Article
- Keywords:
Pancreatectomy;
Organ-Preserving;
Low-Grade Malignant
- MeSH:
Adult;
Aged;
Female;
Follow-Up Studies;
Humans;
Male;
Middle Aged;
*Pancreatectomy;
Pancreatic Neoplasms/diagnosis/*surgery;
Postoperative Complications;
Suture Techniques;
Treatment Outcome
- From:Journal of Korean Medical Science
2010;25(1):97-103
- CountryRepublic of Korea
- Language:English
-
Abstract:
The clinical usefulness of organ-preserving pancreatectomy is not well established due to technical difficulty and ambiguity of functional merit. The purpose of this study is to evaluate the clinical efficacy of organ-preserving pancreatectomy such as duodenum-preserving resection of the head of the pancreas (DPRHP), pancreatic head resection with segmental duodenectomy (PHRSD), central pancreatectomy (CP) and spleen-preserving distal pancreatectomy (SPDP). Between 1995 and 2007, the DPRHP were performed in 14 patients, the PHRSD in 16 patients, the CP in 13 patients, and the SPDP in 45 patients for preoperatively diagnosed benign lesions or tumors with low-grade malignant potential. The clinical outcomes including surgical details, postoperative complications and long-term functional outcomes were compared between organ-preserving pancreatectomy and conventional pancreatectomy group. Major postoperative complications constituted the following: bile duct stricture (7.1% [1/14]) in DPRHP, delayed gastric emptying (31.2% [5/16]) in PHRSD, pancreatic fistula (21.4% [3/14]) in CP. There were no significant differences in postoperative complications and long-term functional outcomes between two groups. Organ-preserving pancreatectomy is associated with tolerable postoperative complications, and good long-term outcome comparing to conventional pancreatectomy. Organ-preserving pancreatectomy could be alternative treatment for benign or low-grade malignant potential lesion of the pancreas or ampullary/parapapillary duodenum.
