Current advance in treatment of fungal keratitis by corneal collagen cross-linking
10.3980/j.issn.1672-5123.2017.7.14
- VernacularTitle:角膜交联疗法治疗真菌性角膜疾病的研究进展
- Author:
Qi, LI
;
Ling-Ling, FU
- Keywords:
fungal keratitis;
ultraviolet A;
riboflavin;
corneal collagen cross-linking
- From:
International Eye Science
2017;17(7):1258-1260
- CountryChina
- Language:Chinese
-
Abstract:
Corneal collagen cross-linking (CXL) is a photochemotherapy for keratoconus, keratectasias and infectious keratitis.Corneal collagen fiber infiltrated with riboflavin, a photosensitizer which generates reactive oxygen species when activated by UVA at 370nm, was induced to form the crosslinks in corneal stroma.Corneal collagen cross-linking alone or combined with medicine therapy could be used to treat fungal keratitis, improve the cure rates, and reduce the complications and the demands of corneal transplantation surgery.The purpose of this paper is to review the basic principle, procedure, laboratory researches, clinical applications and the safety about this treatment.
