Research advances of miR-126 and ophthalmic diseases
10.3980/j.issn.1672-5123.2017.6.14
- VernacularTitle:miR-126与眼科疾病的研究进展
- Author:
Ning-Ning, GAO
;
Fan-Qian, SONG
;
Hong-Yan, GE
- Keywords:
miR-126;
vascular endothelial growth factor;
neovascularization;
immune response
- From:
International Eye Science
2017;17(6):1066-1068
- CountryChina
- Language:Chinese
-
Abstract:
Up to now, a variety of microRNAs have been found in a number of studies, that specifically expressed in retinal neuroepithelial, lens, cornea and retinal pigment epithelium, in which miR-126 plays a certain role in the proliferation of tumor cells, the development of thymus lymphocytes and cardiovascular diseases.Some researches show that miR-126 has certain correlations with the formation of corneal neovascularization, the development of diabetic retinopathy, and the immune system related eye disease.In this paper, the current miR-126 in the role of eye disease mechanism and research progress were reviewed.