Effective scoring function for protein structure prediction
- VernacularTitle:一个有效的蛋白质结构预测评分函数
- Author:
yu-min, ZHANG
;
lu, ZHANG
- Publication Type:Journal Article
- Keywords:
scoring function;
protein structure prediction;
decoy;
potential function
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To design a good scoring function for predicting the tertiary structures of proteins. Methods A scoring function,which was composed of simple sum of pairwise distance-dependent potentials of C?-C?,N-N,C′-C′ and backbone dihedral angle-dependent potentials,was proposed in this paper. Results The performance of the scoring function was verified with experiment to be improved. Conclusion The proposed scoring function is effective and valid in predicting the tertiary structures of proteins.
