Role of inflammation in the relationship between OM and regeneration of optic nerves
10.3980/j.issn.1672-5123.2017.7.17
- VernacularTitle:癌钙调蛋白在炎症反应促视神经再生作用中的研究进展
- Author:
Lin-Kun, MA
;
Xia, CAO
;
Sheng-Ping, LUO
- Keywords:
oncomodulin;
inflammation;
neutrophils;
optic nerve regeneration
- From:
International Eye Science
2017;17(7):1268-1270
- CountryChina
- Language:Chinese
-
Abstract:
Oncomodulin (OM) is known by us progressively as a Calcium binding protein.Recently, OM has been found that it is secreted by inflammatory cells (neutrophilic granulocyte), and a signal which can promote cell growth between innate immunity and neurons, and a key to regenerate the damaged optical nerves by activating inflammation.The function of promoting the regeneration progress of axons has become a hot issue in recent years.This article summarized the mechanism of OM and the relationship between inflammation-induced OM and optic nerve regeneration research and progress were reviewed.