Research progress of intervention treatment on the retinal ischemia-reperfusion injury
10.3760/cma.j.issn.2095-0160.2017.05.016
- VernacularTitle:视网膜缺血-再灌注损伤干预治疗新进展
- Author:
Xue, ZHANG
- Keywords:
Retina;
Ischemia-reperfusion injury;
Intervention treatment
- From:
Chinese Journal of Experimental Ophthalmology
2017;35(5):463-467
- CountryChina
- Language:Chinese
-
Abstract:
Retinal ischemia-reperfusion injury (RIRI) is a common pathological and physiological clinical oculopathy,which can occur in retinal artery and vein occlusion,diabetic retinopathy and acute angle-closure glaucoma.The resulting ischemia can cause cell metabolic dysfunction,serious retinal damage and descending visual function.RIRI is the result of multiple factors.The currently accepted hypotheses mainly include the injury effect of oxygen-derived free radicals,intracellular calcium overload,the action of leucocyte and apoptosis.However the protection and treatment research in the RIRI is limited.The present paper reviews the progression in the drug intervention of RIRI.
