Research advances in cell surface ATP synthase
- VernacularTitle:细胞表面ATP合酶的研究进展
- Author:
Yan, DU
;
Feng, GAO
- Publication Type:Journal Article
- Keywords:
cell surface ATP synthase;
angiogenesis;
tumor inhibition;
lipid metabolism
- From:Journal of Shanghai Jiaotong University(Medical Science)
2009;29(6):741-743,761
- CountryChina
- Language:Chinese
-
Abstract:
Mitochondria ATP synthase is a key enzyme in cellular energy interconversion. It is generally believed that ATP synthase is strictly confined to mitochondria. However, it has been demonstrated that ATP synthase also occurs on the extracellular surface of vascular endothelial cells, tumor cells and adipocytes, instead of normal cells. Based on this characteristic, many functional researches have been conducted on the angiogenesis, tumor inhibition and lipid metabolism, and the mechanism on which this enzyme works has been preliminarily elucidated. The research advances in cell-surface ATP synthase are reviewed in this paper.
