Abnormality on behavioral ability of transgenic mice for HRX-EEN fusion gene
- VernacularTitle:HRX-EEN融合基因转基因小鼠行为能力的异常
- Author:
jun, CAI
;
ai-fen, FU
;
lin, ZHENG
;
guo-hui, FU
- Publication Type:Journal Article
- Keywords:
HRX-EEN fusion gene;
transgenic mice;
Morris water maze
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the abnormality on behavioral ability of transgenic mice for HRX-EEN fusion gene.Methods Transgenic mice for HRX-EEN fusion gene(transgenic group,n=12)and C57/BL mice(control group,n=12)were tested in hidden platform training(day 1 to day 4)and probe trial testing(day 5)in Morris water maze in which ability of spatial learning and retention was assessed.Results In hidden platform training,the latencies of transgenic group were longer than those in control group,and significant differences were observed between the two groups for day 2,3 and 4(P
