Character of breast cancer stromal cells and regulation on tumor cells
- VernacularTitle:乳腺癌间质细胞的特征及其对肿瘤细胞的调控
- Author:
cai-li, SONG
;
ying-chun, XU
;
hong-xia, WANG
;
feng-chun, ZHANG
- Publication Type:Journal Article
- Keywords:
breast cancer;
tumor stromal cells;
tumor cells;
fibroblasts
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Contrary to being an idle bystander,the surrounding tumor microenvironment or stroma,actively participates in,and contributes to tumor progression directly or indirectly.It is evident that tumor stromal cells exhibit specific tumor-suppressive and tumor-promoting abilities that serve to regulate neoplastic growth of the epithelium.Due to the mounting evidence demonstrating the far-reaching effects of stroma during the process of malignant transformation,the involvement of stroma in cancer progression has become an area of intense investigations in recent years.
