Dynamic changes of plasma NPY before and after vascular intracavitary therapy in patients with lower extremity ASO
- VernacularTitle:下肢ASO患者血管腔内治疗前后血浆NPY的动态变化
- Author:
zhi-wei, GAO
;
hao, ZHANG
;
bai-gen, ZHANG
- Publication Type:Journal Article
- Keywords:
neuropeptide Y;
arteriosclerosis obliterans;
ankle-brachial index;
vascular intracavitary therapy
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To dynamically observe the concentrations of plasma neuropeptide Y(NPY)in the patients with lower extremity arteriosclerosis obliterans(ASO)before and after vascular interventional therapy.Methods The levels of plasma NPY were detected by radioimmunoassay in 13 patients with lower extremity ASO(ASO group)before vascular intracavitary therapy and immediately,1 d,3 d and 5 d after vascular intracavitary therapy.Meanwhile,15 healthy subjects were served as control group.Besides,the ankle-brachial indexes(ABI)and clinical staging of ASO group were also obtained and compared before and 3 d after vascular intracavitary therapy.Results Compared with control group,the level of NPY in ASO group was much higher before vascular intracavitary therapy[(250.67?88.27)pg/mL vs(168.40?64.64)pg/mL,P
