Relationship between expression of syndecan-1 and prognosis in pancreatic cancer
- VernacularTitle:Syndecan-1在胰腺癌组织中的表达与预后的关系
- Author:
jun, SHEN
;
zhi-wei, QUAN
;
yong, YANG
;
xiao-hong, YAO
;
ji-yu, LI
- Publication Type:Journal Article
- Keywords:
syndecan-1;
pancreatic cancer;
prognosis;
immunhistochemistry
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the expression of syndecan-1 and the prognosis in pancreatic cancer. Methods The data of 30 patients with pancreatic cancer who received radical operations were retrospectively analysed.Immunohistochemical staining was performed,and the expression of syndecan-1 in tumor epithelial cells and stroma was observed by light microscopy.The relationship between immunohistochemical findings and survival was analysed.Results For those with negative,weak positive,moderate positive and strong positive expression of synecan-1 in tumor epithelial cells and stroma,there were significant differences in the case numbers between those survived for 1 to 2 years and those survived for 2 to 4 years(P