Clinical significance of serum VEGF and bFGF detection in patients with non-small cell lung cancer
- VernacularTitle:非小细胞肺癌患者血清VEGF和bFGF检测的临床意义
- Author:
Ai-qin, GU
;
Bao-hui, HAN
;
Xue-yan, ZHANG
;
Guo-liang, BAO
;
Yu, XIN
;
Yi-yi, SONG
;
Wei-jing, MIAO
- Publication Type:Journal Article
- Keywords:
non-small cell lung cancer;
vascular endothelial growth factor;
basic fibroblast growth factor
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the levels of serum vascular endothelial growth factor(VEGF) and basic fibroblast growth factor(bFGF) in patients with non-small cell lung cancer(NSCLC) and relationships with c1inicopatho1ogica1 characteristics and their clinical significance. Methods The concentrations of serum VEGF and bFGF were detected by enzyme-linked immunosorbent assay(ELISA) in 40 patients with NSCLC before and after chemotherapy. Results The level of serum VEGF in patients with Ⅳ stage NSCLC was significantly higher than that of Ⅲ stage(P