Relationship between Leu72Met polymorphism of Preproghrelin gene and type 2 diabetes mellitus and diabetic nephropathy
- VernacularTitle:Preproghrelin基因Leu72Met多态性与T2DM和DN的关系
- Author:
jia-mei, JIANG
;
yong-ning, SUN
;
li-mei, LIU
;
tai-shan, ZHENG
;
nian-song, WANG
;
feng, WANG
- Publication Type:Journal Article
- Keywords:
type 2 diabetes mellitus;
diabetic nephropathy;
Preproghrelin gene;
Leu72Met polymorphism
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusion Preproghrelin-Leu72Met is not significantly associated with T2DM and DN in Shanghai Han populations,while T2DM with AA genotype is characterized by significant declination in urine microalbumin when compared with CA and CC genotypes.Leu72Met polymorphism(C→A)may postpone the development of microalbuminuria in T2DM subjects.
