Cefepime-Induced Nonconvulsive Status Epileticus Presenting as Coma in a Patient with ESRD on Hemodialysis.
- Author:
Cho I LEE
1
;
Mi Jin HONG
;
Sung Chul HONG
;
Jung Hee PARK
;
Eugene PARK
;
Jang Soo HAN
;
Young Jin KIM
;
Jong Ho LEE
;
Jung Hwan PARK
;
Jong Oh SONG
;
Young Il JO
Author Information
1. Division of Nephrology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea. nephjo@kuh.ac.kr
- Publication Type:Case Report
- Keywords:
Cefepime;
Nonconvulsive status epilepticus;
Hemodialysis
- MeSH:
Aged;
Anticonvulsants;
Aphasia;
Cephalosporins;
Coma;
Electroencephalography;
Epidural Abscess;
Humans;
Kidney Failure, Chronic;
Renal Dialysis;
Renal Insufficiency;
Status Epilepticus
- From:Korean Journal of Nephrology
2011;30(5):537-541
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cefepime-induced nonconvulsive status epilepticus (NCSE) in end-stage renal disease (ESRD) patients receiving hemodialysis has only rarely been reported. Here we report a case of cefepime-induced NCSE presenting as coma in a patient with ESRD on hemodialysis. A 73-year-old man, who had been receiving maintenance hemodialysis, developed aphasia and coma during cefepime therapy for epidural abscess. Emergent eletroencephalography (EEG) revealed evidence of NCSE. The abnormal EEG findings were resolved and comatose mentality was completely recovered after cessation of cefepime and administration of anticonvulsive drugs. Cefepime-induced NCSE should be considered if neurological symptoms including comatose mentality develops during cefepime therapy in a patient with renal failure.
