Clinical study of flow-mediated dilatation of brachial artery in elder patients with isolated systolic hypertension combined with hyperlipidemia
- VernacularTitle:老年单纯收缩期高血压合并高脂血症肱动脉内皮功能研究
- Author:
li, WANG
;
tian, GAO
;
hai-ya, WANG
- Publication Type:Journal Article
- Keywords:
elderly;
systolic hypertension;
endothelium function;
cardiovascular risk factors
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between flow-mediated dilatation of the brachial artery(FMD) and cardiovascular risk factors as well as target organ damage in elder patients with isolated systolic hypertension(ISH).Methods Ninety patients with ISH were divided into two groups: ISH group(n=51) and ISH with hyperlipidemia group(n=39).Color Doppler ultrasound for FMD was performed on all the patients,and carotid artery ultrasound and cardiac ultrasound were also conducted. Results Patiens with hyperlipidemia had lower FMD than those of ISH group(P=0.021).It was revealed by univariate analysis that FMD was negatively related to systolic blood pressure,carotid intima-media thickness and total cholesterol(P
