Electrocolposcopic and thinprep cytologic test in diagnosis of subclinical human papillomavirus infection and cervical intraepithelial neoplasia
- VernacularTitle:电子阴道镜联合新柏氏膜式液基细胞学检测诊断宫颈人乳头瘤病毒亚临床感染和宫颈上皮内瘤变
- Author:
ling, HAN
;
li-hua, LU
;
yue-zhen, XUE
- Publication Type:Journal Article
- Keywords:
subclinical human papillomavirus infection;
cervical intraepithelial neoplasias;
electronic colposcope;
thinprep cytologic test
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of thinprep cytologic test(TCT) and electronic colposcope(EC) examination in patients with subclinical human papillomavirus(HPV) infection(SPI) and cervical intraepithelial neoplasia(CIN),and explore its concordance with pathologic diagnosis. Methods A total of 1 125 females were examined with TCT,744 of whom diagnosed with abnormality by TCT or suspect of cervical lesions were examined with EC,and multiple punch biopsies were performed in 706 of those with abnomal EC images and suspected diseases. ResultsThe sensitivity of TCT,EC examination and the combined examination of TCT and EC for SPI and CIN were 88.74%,88.79% and 90.63%,respectively,the specificity 85.44%,80.38% and 96.41%,respectively,the positive predictive value 74.06%,68.90% and 91.10%,respectively,and the negative predictive value 94.19%,93.61% and 96.21%,respectively.By the combination of the two examinations,the specificity and positive predictive value were significantly increased(P
