Effect of ACEI on Insulin Sensitivity of Acute Myocardial Infarction Treated with Thrombolytic Therapy
- VernacularTitle:ACEI对急性心肌梗死溶栓治疗时胰岛素敏感性的影响
- Author:
jing, SHENG
;
jin-rong, LOU
;
wen-wei, CAI
- Publication Type:Journal Article
- Keywords:
angiotensin-converting enzyme inhibitor;
insulin sensitivity;
acute myocardial infarction;
thrombolytic treatment
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of angiotensin-converting enzyme inhibitor(ACEI) on insulin sensiti-(vity) in dogs with acute myocardial infarction(AMI) after thrombolytic treatment. Methods Twenty dogs were made as AMI models and then underwent thrombolytic treatment.The dogs were divided into the control group(n=10) and the captopril group(n=10) randomly.Insulin,plasma glucose,erythrocyte insulin receptor(EIR),nitrogen(NO) and angiotensin Ⅱ(AT Ⅱ) were(detected) and insulin sensitivity index(ISI) was calculated.The changes of these values in the two groups were contrasted. Results After reperfusion for 120 min,in the control group,ISI and AT Ⅱgot much more rise while EIR and NO fell much more(P
