Relativity between serum vascular endothelial growth factor and its receptors and uterine myoma
- VernacularTitle:血清血管内皮生长因子及其受体水平与子宫肌瘤的相关性
- Author:
yi-cun, ZHONG
;
wei-ping, LI
;
chuan-wei, DING
- Publication Type:Journal Article
- Keywords:
uterine myoma;
vascular endothelial growth factor;
receptor
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relativity between serum vascular endothelial growth factor(sVEGF),its receptors(sVEGFR1 and sVEGFR2) and uterine myoma. Methods Thirty hospitalized patients with uterine myoma were chosen as the study group and the other healthy women of the same age as control group.The levels of sVEGF,sVEGFR1 and sVEGFR2 of the two groups were determined by using ELISA technology. Results The levels of sVEGF and sVEGFR2 in the study group were much higher than in the control group(P0.05).The levels of sVEGF and sVEGFR2 in women with myoma had no differences during the menstrual cycle.The level of sVEGFR2 was correlated with the number of myoma(P