Effects of gel gatifloxacin versus levofloxacin in treatment of bacterial conjunctivitis
- VernacularTitle:加替沙星与左氧氟沙星眼用凝胶对细菌性结膜炎的疗效比较
- Author:
ying, ZHU
;
zhao-rong, ZHU
- Publication Type:Journal Article
- Keywords:
gatifloxacin;
levofloxacin;
bacterial conjunctivitis;
double-blind randomized contrast
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the clinical effectiveness and safety of gatifloxacin gel to bacterial conjunctivitis. Methods Double-blind and random selection were designed for the study,with levofloxacin gel as the control medicine.Thirty-six eyes of the experimental group and 36 of the control group were eligible for evaluation.Each eye received the gel one drop a time and three times per day.The gels were applied to the conjunctiva sac for 7 d. Results The clinic effectiveness of experimental group and control group were 88.89% and 91.67%,which indicated no significant difference.Microbial eradication rates were 90.48% and 93.75%,no significant difference either.Safety composite scores were similar between groups. Conclusion Gatifloxacin ophthalmic gel is safe and effective for treatment of bacterial conjunctivitis,and contains certain clinical value.
