Effects of irradiation of intense pulsed light on the collagen metabolism in human fibroblasts
- VernacularTitle:强脉冲光照射对皮肤成纤维细胞胶原代谢的影响
- Author:
jin, MA
;
shi-ming, GAO
;
zhi-hong, FAN
- Publication Type:Journal Article
- Keywords:
intense pulse light;
fibroblast;
3H-proline incorporation
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of intense pulsed light(IPL) on the collagen metabolism in human fibroblasts.Methods The callan foreskin fibroblasts were cultured and treated with different wave length and designed dose of IPL irradiation(590-1 200 nm,and 29 J/cm2),while 10 without IPL irradiation as controls.By culturing 1,12,24 and 48 h after the irradiation,the synthesis of collagen was measured by 3H-proline incorporation determination. Results The synthesis of collagen activity increased significantly(P
