Pulmonary membrane diffusing capacity and pulmonary capillary blood volume in patients with stable COPD
- VernacularTitle:稳定期COPD患者肺膜弥散和肺毛细血管床容量的改变
- Author:
bei-lan, GAO
;
jin-ming, LIU
;
wen-lan, YANG
;
dong, ZHU
;
ying-min, WANG
- Publication Type:Journal Article
- Keywords:
chronic obstructive pulmonary disease;
diffusion capacity for carbon monoxide of lung;
membrane diffusing capacity;
pulmonary capillary blood volume
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance of pulmonary membrane diffusing capacity(Dm) and pulmonary capillary blood volume(Vc) in patients with stable chronic obstructive pulmonary disease(COPD). Methods Spirometry was performed in 38 patients with stable COPD and 35 healthy individuals in resting condition.The changes of pulmonary parameters were obtained and compared between groups. Results Spirometry test revealed that the percent predicted forced expired volume in one second(FEV1),FEV1/forced volume capacity(FVC)and the percent predicted maximal ventilatory volume(MVV) were declined from stage Ⅰin patients with COPD in comparison with healthy individuals,while diffusing capacity for carbon monoxide of lung(DLCO),carbon monoxide diffusing capacity per liter of alveolar(DLCO/VA),Dm and Vc were declined from stage Ⅱ.Dm in patients with COPD of stageⅠwas sig-nificantly decreased compared with the controls,while Vc was increased compared with the controls(both P
