Relationship between Pro198Leu polymorphism of GPx-1 gene and type 2 diabetes mellitus and diabetic coronary heart disease
- VernacularTitle:GPx-1基因Pro198Leu多态与2型糖尿病及合并冠心病的关系
- Author:
wen-rui, ZHOU
;
li-mei, LIU
;
tai-shan, ZHENG
;
meng, WEI
- Publication Type:Journal Article
- Keywords:
type 2 diabetes mellitus;
coronary heart disease;
glutathione peroxidase-1 gene;
Pro198Leu polymorphism
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).Genotype CT frequency in T2DM group was significantly increased when compared with non-DM control group(P=0.012,OR=2.254).Conclusion Pro198Leu polymorphism of GPX-1 gene increases the risk of type 2 diabetes in Han Chinese of Shanghai,while T allele is not a risk factor of diabetic CHD.
