Lactic acid levels and related influencing factors in type 2 diabetes with normal renal function
- VernacularTitle:肾功能正常的2型糖尿病患者血乳酸水平的变化及影响因素
- Author:
fang, LIU
;
jun-xi, LU
;
jun-ling, TANG
;
xu-hong, HOU
;
jing, WANG
;
jue, LI
;
wei-ping, JIA
;
kun-san, XIANG
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
lactic acid;
creatinine;
body mass index
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05),while hyperlactacidemia existed in 21 patients(4.62%).LA levels increased with the creatinine levels,especially in those with Cr more than 90 ?mol/L.However,LA levels increased with the reduction of GFR,especially in those with GFR less than 80 mL/min.It was revealed by correlation analysis that LA level was positively correlated with Cr,ALT and BMI.The optimal cutoff of Cr inducing the lactic acidemia was 95.35 ?mol/L.Conclusion The baseline LA levels of patients with T2DM are similar to those of healthy adults,and LA levels are mainly influenced by BMI and renal and hepatic function.Hyperlactacidemia may be induced when Cr reaches a level more than 95 ?mol/L.
