Advances in cell components of bioartificial liver
- VernacularTitle:生物人工肝细胞材料研究进展
- Author:
bao-san, HAN
;
bai-yong, SHEN
;
cheng-hong, PENG
;
hong-wei, LI
- Publication Type:Journal Article
- Keywords:
bioartificial liver;
hepatocytes;
hepatic failure;
liver transplantation
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
The biological artificial liver(BAL) can offer reliable artificial liver support for the patients with hepatic failure.All BAL devices contain hepatocytes as their biological component,whose specific biological characteristics contribute to the function of the BAL.During the past two decades,various cells including human hepatocytes,heterogeneous hepatocytes and liver cell lines have been used and different culture methods have been studied to optimize the activity of the biological component.However,both functionality and safety of these cells should be improved before successful use in BAL. This paper summarizes the latest progress on it.
