Application of UMSARS-Ⅰ in evaluation of illness severity in patients with multiple system atrophy
- VernacularTitle:UMSARS-Ⅰ量表在MSA患者病情评价中的应用
- Author:
xiao-jin, ZHANG
;
yi-wen, WU
;
sheng-di, CHEN
- Publication Type:Journal Article
- Keywords:
multiple system atrophy;
unified multiple system atrophy rating scale,section Ⅰ;
reliability;
validity;
sensitivity to change
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the reliability of a novel rating scale, unified multiple system atrophy rating scale, section Ⅰ(UMSARS-Ⅰ) in the evaluation of illness severity in patients with multiple system atrophy (MSA). Methods A retrospective analysis and a prospective follow-up study were conducted by using UMSARS-Ⅰ in 46 patients with MSA, and the Schwab and England scale was employed and illness severity was graded. The reliability, validity and sensitivity to change of UMSARS-Ⅰ in evaluating the illness severity of MSA were estimated. Results UMSARS-Ⅰ enjoyed high internal consistency (standard Crohnbach's ?=0.88) and sound content, criterion-related, construct and discriminant validity in the evaluation of illness severity of MSA, and a moderate sensiti-vity to change was found(effect size=0.61). Conclusion UMSARS-Ⅰ is a reliable and multidimensional semi-quantitative scale in the measurement of severity and progression of impairment in MSA.
