Expression of estrogen receptor,progesterone recptor and c-erbB-2 in breast cancer tissues
- VernacularTitle:乳腺癌组织雌激素和孕激素受体及c-erbB-2的表达
- Author:
li, SUN
;
ying-chun, XU
;
feng-chun, ZHANG
- Publication Type:Journal Article
- Keywords:
estrogen receptor;
progesterone receptor;
c-erbB-2;
breast cancer
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of estrogen receptor (ER), progesterone recptor (PR) and c-erbB-2 in breast cancer tissues and its relationship with prognostic factors. Methods The clinical data of 1 008 cases with breast cancer were retrospectively analysed. The relationship between the expression of ER, PR and c-erbB-2 in breast cancer tissues and the prognostic factors such as menopausal status, axillary lymph nodes metastasis and TNM stage was investigated. Results The mean presentation age of the 1 008 cases was (53.53?12.60) years. Invasive ductal cancer was the most common pathological type (80.5%). Postmenopausal ER-positive cases were significantly more than premenopausal ER-positive ones, and the clinical stage was lower (P
