Regulatory dendritic cell therapy in organ transplantation
- VernacularTitle:调节性树突状细胞治疗在器官移植应用
- Author:
kai, YAO
;
guo-hai, SHI
;
xiang-hui, WANG
- Publication Type:Journal Article
- Keywords:
dendritic cells;
organ transplantation;
clinical application
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Dendritic cells (DCs) are uniquely well-equipped antigen (Ag)-presenting cells. This function of DCs, coupled with their remarkable plasticity, renders them attractive therapeutic targets for immune modulation. Recent data have demonstrated a promising role for pharmacologic treatment as a means of generating potent regulatory DCs. Herein, the evidence that the potential of regulatory DC the-rapy is considerable and that there are compelling reasons to evaluate it in the setting of organ transplantation in the near future are discussed in this paper.
