Clinicopathological study of lymph node micrometastasis in patients with early gastric cancer
- VernacularTitle:早期胃癌淋巴结微转移的临床病理
- Author:
xiao-yan, WANG
;
ren-da, BI
;
xiao-long, JIN
;
zheng-gang, ZHU
- Publication Type:Journal Article
- Keywords:
early gastric cancer;
lymph node;
micrometastases;
prognosis;
immunohistochemistry;
cytokeratin
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between lymph node micrometastasis in early gastric cancer and clinicopathology of tumor,and explore an appropriate operative procedure.Methods A total of 1 004 lymph nodes from 50 patients with early gastric cancer(EGC)were sliced and restained with H.E and immunohistochemical technique,respectively.Immunohistochemical staining was performed by the streptavidin-biotin immunoperoxidase method with cytokeratin-specific monoclonal antibody CAM5.2.The relationship between lymph node micrometastasis and clinicopathological characteristics of primary tumors and prognosis of EGC was analysed.Results The incidence of nodal micro-involvement was significantly increased in diffuse type cancerous lesions(n=11,32.35%)as compared with intestinal type cancerous lesions(n=1,6.25%)(P
