Effects of lipid microspheres prostaglandin E1 on microcirculation deficit of subarachnoid hemorrhage
- VernacularTitle:Lipo PGE1治疗蛛网膜下腔出血后脑微循环障碍的改善
- Author:
li, WEN
;
shan-quan, LI
;
jiong, DAI
- Publication Type:Journal Article
- Keywords:
prostaglandin E1;
subarachnoid hemorrhage;
cerebral vasospasm
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of lipid microspheres prostaglandin E1(Lipo PGE1) on subarachnoid hemorrhage(SAH).Methods Ninty-three patients with SAH were randomly divided into control group(treated with nomal drugs) and Lipo PGE1 treatment group(treated with nomal drugs and Lipo PGE1).Changes in neuroimaging,biochemical indexes and incidence of cerebral vasospasm were measured. Results A lower incidence rate of cerebral vasospasm was observed in Lipo PGE1 treatment group(P0.05).The levels of vWF and GMP-140 were significant lower in the Lipo PGE1 treatment group than those in the control group after treatment for 3 and 7 d(P
