Expression of Human Kallikrein Gene 4 and 5 in Ovarian Cancer
- VernacularTitle:人类激肽释放酶基因4、5在卵巢癌中的表达
- Author:
xin-hua, CHEN
;
chen-min, YANG
;
qing, SHI
- Publication Type:Journal Article
- Keywords:
ovarian cancer;
kallikrein gene 4;
kallikrein gene 5;
quantitative RT-PCR
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of human kallikrein gene(KLK) 4 and KLK5 in ovarian cancers,and to investigate the pathogenesis in malignant tumors. Methods Fifty specimens of ovarian cancers were divided into three groups: malignant tumor group(n=23),borderline tumor group(n=6) and control group(normal or benign tumor,n=21).Fluorescent quantitative RT-PCR was employed to determine the expression of KLK4 and KLK5 in these specimens. Results The expression of KLK4 in ovarian cancers was significantly higher than that of the control group(P
