Association of HLA-DR/DQ with Oral Lichen Planus
- VernacularTitle:HLA-DR和HLA-DQ等位基因与口腔扁平苔藓的相关性
- Author:
hui-yuan, LI
;
ling-di, XU
;
guo-yao, TANG
- Publication Type:Journal Article
- Keywords:
oral lichen planus;
human leukocytes antigen;
allele
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association of human leukocytes antigen(HLA)-DR/DQ with oral lichen planus(OLP) in the area of Yangtze River Delta. Methods HLA-DRB1 and DQB1 genotyping of 44 unrelated OLP patients and 150 normal controls were performed by polymerase chain reaction-sequence specific primers(PCR-SSP) method.The data were compared between the OLP group and normal controls,and between different types of OLP patients. Results The frequency of HLA-DRB1*09 and HLA-DRB1*07 alleles were significantly higher in OLP group than those in normal controls(56.8% vs 31.3% and 27.3% vs 13.3%,P
