Comparative Evaluation of Periprostatic Nerve Block with and without Intraprostatic Nerve Block in Transrectal Ultrasound-Guided Prostatic Needle Biopsy.
10.4111/kju.2012.53.8.547
- Author:
Santosh Kumar SINGH
1
;
Ashok KUMAR
;
Mahavir Singh GRIWAN
;
Jyotsna SEN
Author Information
1. Department of Urology, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak, India.
- Publication Type:Randomized Controlled Trial ; Original Article
- Keywords:
Analgesia;
Lignocaine
- MeSH:
Analgesia;
Biopsy;
Biopsy, Needle;
Humans;
Lidocaine;
Needles;
Nerve Block;
Prospective Studies;
Prostate;
Prostate-Specific Antigen
- From:Korean Journal of Urology
2012;53(8):547-551
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Controversy exists over the pain during prostate biopsy. Periprostatic nerve block is a commonly used anaesthetic technique during transrectal ultrasound (TRUS)-guided prostate biopsy. The recent trend toward increasing the number of cores has become popular. This practice further increases the need for a proper anaesthetic application. We compared the efficacy of periprostatic nerve block with or without intraprostatic nerve block. MATERIALS AND METHODS: We conducted a prospective double-blinded placebo-controlled study at our institute with 142 consecutive patients. Patients were randomly assigned into 3 groups. Group 1 received periprostatic nerve block with intraprostatic nerve block with 1% lignocaine. Group 2 patients were administered periprostatic nerve block only with 1% lignocaine. Group 3 received no anaesthesia. Patients were asked to grade their level of pain by using an 11-point linear analogue scale at the time of ultrasound probe insertion, at the time of anaesthesia, during biopsy, and 30 minutes after biopsy. RESULTS: The study groups were comparable in demographic profile, prostate-specific antigen (PSA) level, and prostate size. The mean pain scores at the time of biopsy in groups 1, 2, and 3 were 2.70, 3.39, and 4.16, respectively. Group 1 recorded the minimum mean pain score of 2.70 during prostate biopsy, which was significantly lower than the scores of groups 2 and 3 (p<0.001). There were no significant differences in pain scores among the 3 groups during probe insertion, during anaesthesia, or at 30 minutes after biopsy (p>0.05). CONCLUSIONS: Periprostatic nerve block with intraprostatic nerve block provides better pain control than does periprostatic nerve block alone in TRUS-guided prostate biopsy.
