Regulating Proteins Participating in Neurotransmitter Release of Synaptic Vesicles at Nerve Terminals
- VernacularTitle:神经末梢突触囊泡相关的调节蛋白
- Author:
rui, ZHENG
;
hai-yan, ZHOU
;
sheng-di, CHEN
- Publication Type:Journal Article
- Keywords:
neurotransmitter;
synaptic vesicle;
regulating protein;
soluble N-ethylmaleimide-sensitive(factor-attachment) protein receptors complex
- From:Journal of Shanghai Jiaotong University(Medical Science)
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Neurotransmitter release is controlled by groups of proteins associated with the membranes of synaptic vesicles and the presynaptic membranes.It is a highly dynamic process which is spatially and temporally regulated via a cascade of protein-protein interactions.These proteins participate in each step of the synaptic vesicle circulation at nerve terminals including the formation of soluble N-ethylmaleimide-sensitive factor-attachment protein receptors complex,the targeted trafficking of synaptic vesicles,the vesicle docking,the neurotransmitter release and finally the reuse of the proteins.This article focuses on the physiological function and the interactions of these regulating proteins.
